As Highly Pathogenic Avian Influenza A(H5N1) spreads quickly to new species and new regions, its potential threat to humans — and to business operations — is coming into sharper focus.

Bird flu is making headlines: the virus has now been detected on poultry farms in 48 of America’s 50 states and, most recently, in 33 dairy cow herds across 8 states. Here’s what you need to know.